Precise Cell Annotation Services

1. Surpassing Manual Annotation Limits for Precise Identification of Complex Cells

We adopt mIF + H&E dual staining + AI analysis technology to overcome challenges that traditional pathology cannot address:

• Precise differentiation of lymphocyte subsets: Through multi-target mIF staining (e.g., CD3+ T cells and CD20+ B cells) combined with AI spatial co-localization analysis, lymphocyte subsets are accurately distinguished in H&E-stained sections (accuracy > 95%).

• Dynamic recognition of cell states: Integrating functional markers (Ki-67/Cleaved Caspase-3/PD-1) with morphological features, AI automatically quantifies states such as apoptosis, proliferation, and exhaustion.

• Efficient capture of rare cells: AI, via million-level cell scanning and weak signal enhancement algorithms, achieves a detection sensitivity of 0.1% (easily missed by manual inspection).

2. Dual Staining Technology for Ultra-High Precision

• Dual staining technology: Cells stained with H&E are annotated via mIF staining.

• Objective cell annotation technology: Not based on the subjective annotation of pathologists.

• mIF-specific labeling: Precisely identifies target cells (e.g., tumor cells, immune cells).

• H&E morphological verification: Dual validation ensures annotation reliability.

• AI automatic registration: Eliminates staining position deviations with an accuracy of > 98%.

3. High Cost-Effectiveness, Saving 50% of Costs

• AI automation: Reduces manual time by 80%.

• Batch processing: Capable of completing annotation and analysis of 200+ samples per day.

• Flexible customization: Supports special labeling schemes and data analysis requirements.

Technical Advantages

• Objective cell annotation technology: Not based on the subjective annotation of pathologists.

• Multi-dimensional verification: Dual confirmation with molecular markers + morphology.

• Intelligent anti-interference: Automatically corrects issues like uneven staining and tissue folding.

• Traceable standards: Fully digitalized process with reproducible results.

Typical Cases

• Assisted a research team in annotating over 18 cell types, 70 million cells, and 30 tissue types.

• A pharmaceutical company completed drug screening analysis of 1000+ samples in 5 days (traditionally requiring 3 weeks).